Use of the PAQLQ Questionnaire and Spirometry to Assess the Control of Asthma in Adolescents
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Abstract
The objective: was to investigate the level of asthma control in adolescents using the PAQLQ questionnaire and spirometry.
Materials and methods. The study included 60 adolescents aged 12 to 18 years, patients with asthma, without clinical and functional signs of exacerbation. 43.4% of adolescents (26 people) had a controlled course, and 56.6% of children (34 people) had a partially controlled asthma.
Results. According to the results of bronchodilation tests 3 times more often showed a positive response when using a combined bronchodilator, compared with salbutamol (χ2y=4.37; p=0,04). The average increase in FEV1 was 1,4 times greater in children after the use of ipratropium bromide / fenoterol – 8,9±0,8%, compared with the results of the test using salbutamol – 6,2±0,6% (p<0,05).
After evaluating the results of spirometry, the proportion of children with incomplete asthma control was 63,3%. Detected 38,5% of patients with a total QOL PAQLQ <6 points in controlled asthma. After conducting a survey on the PAQLQ questionnaire and spirometric examination, the percentage of children with incomplete control of asthma increased 1,6 times from 43,3% to 73,3% (χ2=11,1; p<0,05).
Conclusion. Clinical monitoring is not always sufficient to properly assess the level of asthma control in adolescents. Consideration of several assessment methods makes it possible to more accurately determine the level of asthma control in a patient.
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References
The Global Asthma Report 2018. URL: http://www.globalasthmareport.org.
Global Burden of Disease due to Asthma. URL: http://globalasthmareport.org/burden/burden.php.
Szefler S, Chipps B. Challenges in the treatment of asthma in children and adolescents. Ann. Allergy Asthma Immunollogy. 2018;120(4):382-8. DOI: https://doi.org/10.1016/j.anai.2018.01.003
Barreto V, Simões S, Fernandes B, Conceição F, Fernandes T, Varjão A, Santos S, Franco J. Pulmonary function and symptoms in asthmatics adolescents. World Allergy Organization Journal. 2015;8(1):266. https://doi.org/10.1186/1939-4551-8-S1-A266
Demoly P.et al. Repeated cross-sectional survey of patient-reported asthma control in Europe in the past 5 years. Eur. Respir. Rev. 2012;21(123):66-74. https://doi.org/10.1183/09059180.00008111
Serrano C.et al. Guidelines for severe uncontrolled asthma. Arch. Bronconeumol. 2015;51(5): 235-46. https://doi.org/10.1016/j.arbres.2014.12.007
Belay IM, Raznatovskaya EN, Gritsova NA, Reznichenko YG. Clinical pharmacology of bronchodilators: tutorial. Zaporozhye, ZDMU. 2014. 70 p.
Statistical Book 2017 (published on July 05, 2018, updated on July 11, 2018) URL: https://www.rosminzdrav.ru/ministry/61/22/stranitsa-979/statisticheskiei-informatsionnye-materialy/statisticheskiy-sbornik-2017-god
Follenweider L., Lambertino A. Epidemiology of asthma in the United States. Nurs Clin. North Am. 2013;48(1):1-10. https://doi.org/10.1016/j.cnur.2012.12.008
O’Byrne P., Jenkins C., Bateman E. The paradoxes of asthma management: time for a new approach? Eur. Respir. J. 2017;50(3):1-8. https://doi.org/10.1183/13993003.01103-2017
Cooper B. G.et al. The Global Lung Function Initiative (GLI) Network: bringing the world’s respiratory reference values together. Breathe (Sheff). 2017;13(3):56-64. https://doi.org/10.1183/20734735.012717
Alferov VP, Aleksandrovich IV, Aleksandrovich Yu. S. Quality of life and social adaptation of children with bronchial asthma. Russian Family Doctor. 2005;9(2):41-46.
Shakhova OO., Sichkar IB. Assessment of the control of bronchial asthma in the period of clinical well-being in children who have fallen asleep due to the variability of bronchial inflammation. Bukovynskyi Medical Visitor. 2014;18(2):120-3.
Drakina SA., Perevoshchikova NK., Chernykh NS., Torochkina GP. Restoration of control over the course of bronchial asthma, taking into account the personality traits of adolescents’ bones. Mother and Child. 2019;1:31-36.
Okhotnikova OM., Besh LV., Umanets TR. Bronchial asthma in pediatric practice: a glance of provincial specialties. Health of Ukraine. Pediatrics. 2017;2:20-21.
Guidelines for the Diagnosis and Management of Asthma (EPR-3). (Update 2019) URL : https://www.nhlbi.nih.gov/health-pro/guidelines/current/asthma-guidelines
Wilson SR. et al. Asthma Outcomes: Quality of Life. J. Allergy Clin. Immunol. 2012;129(3):88-123. https://doi.org/10.1016/j.jaci.2011.12.988
Kuzina EN., Spivak EM. Quality of life in mild bronchial asthma in children. Medical psychology in Russia: Electron. Scientific. Zhurn. 2017;T.9,6(47). URL: http://mprj.ru (date of the date: 09.09.2020).
PAQLQ(S) – Standardised Paediatric Asthma Quality Of Life Questionnaire [cited 2020 Sep 9]. URL: https://www.qoltech.co.uk/paqlq_s.html
Juniper EF. Health-related quality of life in asthma. Curr. Opin. Pulm. Med. 1999;5(2):105-110. https://doi.org/10.1097/00063198-199903000-00005
O’Byrne PM. et al. Measuring asthma control: a comparison of three classification systems. European Respiratory Journal. 2010;36(2):269-76.
Brian L. et al. Standardization of Spirometry 2019 Update. An Official American Thoracic Society and European Respiratory Society Technical Statement. American Journal of Respiratory and Critical Care Medicine. 2019;200(8):70-88. https://doi.org/10.1164/rccm.201908-1590ST
