New Possibilities of Correction of Iron Deficiency Conditions in the Practice of a Family Doctor

##plugins.themes.bootstrap3.article.main##

Л. Ф. Матюха

Abstract

The article considers the main causes of iron deficiency and iron deficiency anemia (IDA) in the practice of a family doctor, in particular – conditions accompanied by a significant increase in the physiological need for iron. Special attention is paid to the clinical aspects of iron deficiency and IDA in women of reproductive age. Differences in the absorption of heme and non-heme iron are described. The advantages of prevention and dietary correction of iron deficiency conditions using a combination of heme iron and ferrous sulfate (Richter FerroBio) are revealed, taking into account the importance of tolerability and safety issues for patients.

##plugins.themes.bootstrap3.article.details##

How to Cite
Матюха, Л. Ф. (2020). New Possibilities of Correction of Iron Deficiency Conditions in the Practice of a Family Doctor. Family Medicine, (1-2), 99–102. https://doi.org/10.30841/2307-5112.1-2.2020.204547
Section
General medicine
Author Biography

Л. Ф. Матюха, P.L. Shupyk National Medical Academy of Postgraduate Education

Larysa F. Matіukha,

Head of Department of Family Medicine and Outpatient Care

References

Колосова Н.Г., Баяндина Г.Н., Машукова Н.Г., Геппе Н.А.. Обмен железа в организме и пути коррекции его нарушений // Трудный пациент». – 2011. – Т. 9. – № 8–9. – С. 54–58.

Романова А.Ф., Выговская Я.И., Логинский В.Е., Дягиль И.С., Абраменко И.В. Справочник по гематологии. – К.: Здоров’я, 1997. – 324 с.

Camaschella C. Iron deficiency. Blood. 2019;133(1):30-39.

Kassebaum NJ, Jasrasaria R, Naghavi M, et al. A systematic analysis of global anemia burden from 1990 to 2010. Blood. 2014; 123(5):615-624.

Kiss JE, Vassallo RR. How do we manage iron deficiency after blood donation? Br J Haematol. 2018;181(5):590-603.

Васильева Т.М., Захарова И.Н., Заплатников А.Л., Лазарева С.И., Мачнева Е.Б. Алгоритм диагностики и лечения железодефицитных состояний у детей // РМЖ. – 2018. – № 9. – С. 2–7.

Thurnham D.I., McCabe L.D., Haldar S. et al. Adjusting plasma ferritin concentrations to remove the effects of subclinical inflammation in the assessment of iron deficiency: a metaanalysis. Am J Clin Nutr 2010; 92: 3: 546–555.

Cappellini M.D., Comin‐Colet J., de Francisco A., Dignass A., Doehner W. et al. Iron deficiency across chronic inflammatory conditions: International expert opinion on definition, diagnosis, and management. Am J Hematol. 2017 Oct; 92(10): 1068–1078.

Anderson G.J., McLaren G.D. Iron Physiology and Pathophysiology in Humans; Humana Press / Springer:New York, NY, USA, 2012.

Mann J., Truswell S. Essentials of Human Nutrition, 4th ed.; Oxford University Press: Oxford, UK, 2012.

Hallberg L. Iron requirements and bioavailability of dietary iron. In Nutritional Adequacy, Nutrient Availability and Needs; Springer: New York, NY, USA, 1983; pp. 223–24.

Young I., Parker H.M., Rangan A. et al. Association between Haem and Non-Haem IronIntake and Serum Ferritin in Healthy Young Women. Nutrients. 2018 Jan 12;10(1). pii: E81.

Hallberg L., Björn-Rasmussen E., Howard L., Rossander L. Dietary heme iron absorption: A discussion of possible mechanisms for the absorption promoting effect of meat and for the regulation of iron absorption.Scand. J. Gastroenterol.1979,14, 769–779.

Lombardi-Boccia G., Martinez-Dominguez B., Aguzzi A. Total heme and non-heme iron in raw and cooked meats. J. Food Sci.2002,67, 1738–1741.

Rangan A.M., Ho R.W.L., Blight G.D., Binns C.W. Haem iron content of Australian meats and fish. Food Aust.1997, 49, 508–511.

Bjornrasmussen E., Hallberg L., Isaksson B., Arvidsson B. Food ironabsorption in man – Applications of2-pool extrinsic tag method to measure heme and non-heme iron absorption from whole diet. J. Clin. Investig.1974,53, 247–255.

Skolmowska D., Głąbska D. Analysis of Heme and Non-Heme Iron Intake and Iron Dietary Sources in Adolescent Menstruating Females in a National Polish Sample. Nutrients 2019, 11(5), 1049.

Beck K.L., Conlon C.A., Kruger R., Coad J. Dietary determinants of and possible solutions to iron deficiency for young women living in industrialized countries: A review. Nutrients 2014, 6, 3747–3776.

Rangan A., Aitkin I., Blight G., Binns C. Factors affecting iron status in 15–30 year old female students. Asia Pac. J. Clin. Nutr.1997,6, 291–295.

Tolkien Z., Stecher L., Mander A.P., Pereira D.I., Powell J.J. Ferrous sulfate supplementation causes significant gastrointestinal side effects in adults: a systematic review and meta-analysis. PLoS One. 2015;10(2): e0117383.

Girelli D., Ugolini S., Busti F., Marchi G., Castagna A. Modern iron replacement therapy: clinical and pathophysiological insights. Int J Hematol. 2018;107(1):16-30.

Narayanan V., Bhargava A. Realworld efficacy and tolerability of heme iron polypeptide in non-pregnant and pregnant women with iron deficiency anemia. International Journal of Medical Research & Health Sciences, 2018, 7(6): 50-56.

Danko J. et al. Observation of the efficacy and tolerability of iron supplementation using fixed combination of heme iron and iron sulphate (Globifer®), Clinical Nutrition, submitted. ClinicalTrials.gov Identifier: NCT03055559.

Elmahaishi W.M., Zwawa A.A., Elmahaishi A.M., Elmahaishi M.S. The effectiveness and tolerability of Globifer Forte (Haem Iron) tablets on iron deficiency anemia in pregnancy. J Ginecol Reprod Med. 2017; 1(4):1-4.