Prognostic Significance of the Main Cardiovascular Risk Factors in People with Ischemic Heart Disease Over 60 Years of Age

Abstract

The objective: to determine the boundary levels of cardiovascular risk factors influencing the life expectancy of patients with ischemic heart disease (IHD) over the age of 60 years.

Materials and methods. 227 histories of patients with IHD aged 60–87 years, from 1925 to 1944 were born: 107 males and 120 females. All the patients were first hospitalized in the hospital and subsequently observed with the main diagnosis of IHD. Follow-up of patients lasted from 3 to 25 years, until the endpoint was reached or until the last observation in 2017. As the end point, the death of the patient was taken, on the basis of which the life expectancy index (which was determined by the date/age of death) was studied.

Results. As a result of multivariate regression analysis, it has been shown that the main effect on life expectancy of patients with IHD is the presence of hypertension, diabetes and LDL. The threshold level, which has a prognostic value for the life expectancy of patients with coronary heart disease, has a SBP of170 mm Hg (p=0,04599), DBP –85 mm Hg (p=0,00005), the level of LDL-α is 2,9 mmol/L (p=0,00094). In addition, the study shows that in patients over the age of 60 years with IHD and concomitant diabetes, the predictive value of glucose is 9,5 mmol/L (p=0,01266).

Conclusions. It is determined that on the index of life expectancy of patients with IHD of the elderly affects the presence of systolediastolic hypertension, elevated levels of glucose and the level of LDL cholesterol. The threshold level, which has a prognostically significant effect on the life expectancy of elderly patients with IHD for blood pressure is 170/85 mm Hg, for LDL –2,9 mmol/L. Patients older than 60 years of age with IHD and the presence of type 2 diabetes mellitus have a mean glucose level that has a critical life-span of 9,5 mmol/L.