The Effect of the Treatment-and-prophylactic Complex on the Indices of the Function of External Respiration in Patients with Bronchial Asthma Against the Background of Overweight or Obesity

Abstract

Objective: to analyze the effect of the developed treatment-andprophylactic complex (PBL) on the indices of respiratory function in patients with bronchial asthma (BA) on the background of overweight or obesity.

Materials and methods. By design, the study took place in two stages. At the first stage, 105 patients were screened (72 women and 33 men, whose mean age was 41.19 ± 1.05 years) with the main diagnosis of asthma. The second stage included 75 patients (72 women and 33 men, whose average age was 41.19 ± 1.05 years) with asthma against the background of overweight or obesity. All patients were diagnosed according to international consensus documents.

Results. It was found that overweight or obesity is an aggravating factor in BA, since patients of the main group with a severe course had a significantly higher BMI, the percentage of body fat mass than patients of other groups. As a result of evaluating the effectiveness of the developed forestry complex with the inclusion of pharmacological correction along with training in the conditions of the Asthma school against the background of basic therapy in patients with asthma against the background of overweight or obesity, it was found that the main group that used the above mentioned PBM showed the best results asthma-control. A positive trend in asthma control (RRR = 0.75, NNT = 2.12) was established, which is more reliable (p <0.05) than in the comparison group.

Conclusion. Patients with overweight and patients with Npimt did not have significant differences in indicators of respiratory function. In patients who received the proposed therapeutic and prophylactic complex, there was a significant increase in physical activity, namely, an increase in the number of steps that they took during the day (p<0.05).