Development of the Immune Response in Pneumonia Caused Pseudomonas aeruginosa (Part 2)

##plugins.themes.bootstrap3.article.main##

Oleksandr Abaturov
Anna Nikulina

Abstract

In this paper, based on literature data analyzed key role of proinflammatory and anti-inflammatory cytokines in the development of immune response in pneumonia caused by Pseudomonas aeruginosa. Described signaling pathways that induce the production of interferons type I and III involved in the elimination of Pseudomonas aeruginosa.

##plugins.themes.bootstrap3.article.details##

How to Cite
Abaturov, O., & Nikulina, A. (2016). Development of the Immune Response in Pneumonia Caused Pseudomonas aeruginosa (Part 2). Family Medicine, (6), 120–124. https://doi.org/10.30841/2307-5112.6.2016.249564
Section
Pulmonology
Author Biographies

Oleksandr Abaturov, State Establishment «Dnipropetrovsk Medical Academy of Health Ministry of Ukraine»

Oleksandr Ye. Abaturov,

Head of Department of Pediatrics and Medical Genetics

Anna Nikulina, State Establishment «Dnipropetrovsk Medical Academy of Health Ministry of Ukraine»

Hanna O. Nikulina,

Department of Pediatrics and Medical Genetics

References

Абатуров А.Е. Индукция молекулярных механизмов неспецифической защиты респираторного тракта / А.Е. Абатуров, А.П. Волосовец, Е.И. Юлиш // К., Приватна друкарня ФО-II, Сторожук О.В., 2012. – 240 с.

Al Moussawi K. Distinct contributions of interleukin-1α (IL-1α) and IL-1β to innate immune recognition of Pseudomonas aeruginosa in the lung / K. Al Moussawi, B.I. Kazmierczak // Infect Immun. 2014 Oct;82(10):4204-11. doi: 10.1128/IAI.02218-14.

Alves-Filho J.C. Interleukin-33 attenuates sepsis by enhancing neutrophil influx to the site of infection / J.C. Alves-Filho, F. Sônego, F.O. Souto et al // Nat Med. 2010 Jun;16(6):708-12. doi: 10.1038/nm.2156.

Borthwick L.A. The IL-1 cytokine family and its role in inflammation and fibrosis in the lung // Semin Immunopathol. 2016 Jul 38(4):517-34. doi: 10.1007/s00281-016-0559-z.

Boxx G.M. The Roles of Type I Interferon in Bacterial Infection / G.M. Boxx, G. Cheng // Cell Host Microbe. 2016 Jun 8;19(6):760-9. doi: 10.1016/j.chom.2016.05.016.

Broz P. Inflammasome assembly: The wheels are turning // Cell Res. 2015 Dec;25(12):1277-8. doi: 10.1038/cr.2015.137.

Carles M. Heat;shock response increases lung injury caused by Pseudomonas aeruginosa via an interleukin-10-dependent mechanism in mice / M. Carles, B.M. Wagener, M. Lafargue et al // Anesthesiology. 2014 Jun;120(6):1450-62. doi: 10.1097/ALN.0000000000000235.

Carrigan S.O. IFN regulatory factor 3 contributes to the host response during Pseudomonas aeruginosa lung infection in mice / S.O. Carrigan, R. Junkins, Y.J. Yang et al // J Immunol. 2010 Sep 15;185(6): 3602-9. doi: 10.4049/jimmunol.0903429.

Chang J. IL;33 Signaling in Lung Injury / J. Chang, Y.F. Xia, M.Z. Zhang, L.M. Zhang // Transl Perioper Pain Med. 2016;1(2):24-32. PMID: 27536706.

Chmiel J.F. Prolonged inflammatory response to acute Pseudomonas challenge in interleukin-10 knockout mice / J.F. Chmiel, M.W. Konstan, A. Saadane et al // Am J Respir Crit Care Med. 2002 Apr 15;165(8):1176-81. doi: 10.1164/ajrccm.165.8.2107051.

Choi S. TNF-α is a key regulator of MUC1, an anti-inflammatory molecule, during airway Pseudomonas aeruginosa infection / S. Choi, Y.S. Park, T. Koga, A. Treloar, K.C. Kim // Am J Respir Cell Mol Biol. 2011 Feb;44(2):255-60. doi: 10.1165/rcmb.2009-0323OC.

Cohen T.S. Microbial pathogenesis and type III interferons / T.S. Cohen, D. Parker // Cytokine Growth Factor Rev. 2016 Jun;29:45-51. doi: 10.1016/j.cytogfr.2016.02.005.

Cohen T.S. Activation of inflammasome signaling mediates pathology of acute P. aeruginosa pneumonia / T.S. Cohen, A.S. Prince // J Clin Invest. 2013 Apr;123(4):1630-7. doi: 10.1172/JCI66142.

Cohen T.S. Bacterial pathogens activate a common inflammatory pathway through IFNλ regulation of PDCD4 / T.S. Cohen, A.S. Prince // PLoS Pathog. 2013;9(10):e1003682. doi: 10.1371/journal.ppat.1003682.

Cyktor J.C. Interleukin-10 and immunity against prokaryotic and eukaryotic intracellular pathogens / J.C. Cyktor, J. Turner // Infect Immun. 2011 Aug;79(8):2964-73. doi: 10.1128/IAI.00047-11.

Dinarello C.A. Interleukin-18 and IL-18 binding protein / C.A. Dinarello, D. Novick, S. Kim, G. Kaplanski // Front Immunol. 2013 Oct 8;4:289. doi: 10.3389/fimmu.2013.00289.

Dubin P.J. IL-17 in cystic fibrosis: more than just Th17 cells / P.J. Dubin, J.K. Kolls // Am J Respir Crit Care Med. 2011 Jul 15;184(2):155-7. doi: 10.1164/rccm.201104-0617ED.

Farias R. The TAK1>IKKв>TPL2>MKK1/MKK2 Signaling Cascade Regulates IL-33 Expression in Cystic Fibrosis Airway Epithelial Cells Following Infection by Pseudomonas aeruginosa / R. Farias, S. Rousseau // Front Cell Dev Biol. 2016 Jan 11;3:87. doi: 10.3389/fcell.2015.00087.

Faure E. Pseudomonas aeruginosa type-3 secretion system dampens host defense by exploiting the NLRC4;coupled inflammasome / E. Faure, J.B. Mear, K. Faure et al // Am J Respir Crit Care Med. 2014 Apr 1;189(7):799-811. doi: 10.1164/rccm.201307–1358OC.

Hajjar A.M. An essential role for non-bone marrow-derived cells in control of Pseudomonas aeruginosa pneumonia / A.M. Hajjar, H. Harowicz, H.D. Liggitt et al // Am J Respir Cell Mol Biol. 2005 Nov;33(5):470-5. doi: 10.1165/rcmb.2005-0199OC.

Hamming O.J. Lambda Interferons: New Cytokines with Old Functions / O.J. Hamming, H.H. Gad, S. Paludan, R. Hartmann // Pharmaceuticals (Basel). 2010 Mar 25;3(4):795-809. doi: 10.3390/ph3040795.

Hazlett L.D. IL-33 shifts macrophage polarization, promoting resistance against Pseudomonas aeruginosa keratitis / L.D. Hazlett, S.A. McClellan, R.P. Barrett et al // Invest Ophthalmol Vis Sci. 2010 Mar;51(3):1524-32. doi: 10.1167/iovs.09-3983.

Hazlett L.D. IL-10 function, regulation, and in bacterial keratitis / L.D. Hazlett, X. Jiang, S.A. McClellan // J Ocul Pharmacol Ther. 2014 Jun;30(5):373-80. doi: 10.1089/jop.2014.0018.

Hsu D. Interleukin-17 Pathophysiology and Therapeutic Intervention in Cystic Fibrosis Lung Infection and Inflammation / Hsu D., Taylor P., Fletcher D. et al // Infect Immun. 2016 Aug 19;84(9):2410-21. doi: 10.1128/IAI.00284-16.

Huang J. Structural basis of cell apoptosis and necrosis in TNFR signaling / J. Huang, S. Yu, C. Ji, J. Li // Apoptosis. 2015. Feb; 20(2): 210-5. doi: 10.1007/s10495-014-1061-5.

Huang X. IL-18 contributes to host resistance against infection with Pseudomonas aeruginosa through induction of IFN-gamma production / X. Huang, S.A. McClellan, R.P. Barrett, L.D. Hazlett // J Immunol. 2002 Jun 1;168(11):5756-63.doi: 10.4049/jimmunol.168.11.5756.

Kanno E. Neutrophil-derived tumor necrosis factor-α contributes to acute wound healing promoted by N-(3-oxododecanoyl)-L-homoserine lactone from Pseudomonas aeruginosa / E. Kanno, K. Kawakami, S. Miyairi et al // J Dermatol Sci. 2013 May;70(2):130-8. doi: 10.1016/j.jdermsci.2013.01.004.

Kinoshita M. Restoration of natural IgM production from liver B cells by exogenous IL-18 improves the survival of burn-injured mice infected with Pseudomonas aeruginosa / M. Kinoshita, N. Shinomiya, S. Ono et al // J Immunol. 2006 Oct 1;177(7):4627-35. doi: 10.4049/jimmunol.177.7.4627.

Lage S.L. Emerging Concepts about NAIP/NLRC4 Inflammasomes / S.L. Lage, C. Longo, L.M. Branco et al // Front Immunol. 2014 Jul 2;5:309. doi: 10.3389/fimmu.2014.00309.

Lavoie E.G. Innate immune responses to Pseudomonas aeruginosa infection / E.G. Lavoie, T. Wangdi, B.I. Kazmierczak // Microbes Infect. 2011 Dec;13(14;15):1133-45. doi: 10.1016/j.micinf.2011.07.011.

Lee J.H. Modulation of bacterial growth by tumor necrosis factor-alpha in vitro and in vivo / J.H. Lee, L. Del Sorbo, A.A. Khine et al // Am J Respir Crit Care Med. 2003 Dec 15;168(12):1462-70. doi: 10.1164/rccm.200302;303OC.

Li L. Associations between TNF-α polymorphisms and pneumonia: a meta-analysis / L. Li, W. Nie, W. Li, W. Yuan, W. Huang // PLoS One. 2013;8(4):e61039. doi: 10.1371/journal.pone.0061039.

Liew F.Y. Interleukin-33 in health and disease / F.Y. Liew, J.P. Girard, H.R. Turnquist // Nat Rev Immunol. 2016 Sep 19. doi: 10.1038/nri.2016.95.

Liu J. The responses of γδ T-cells against acute Pseudomonas aeruginosa pulmonary infection in mice via interleukin-17 / J. Liu, H. Qu, Q. Li, L. Ye, G. Ma, H. Wan // Pathog Dis. 2013 Jul;68(2):44-51. doi: 10.1111/2049-632X.12043.

Lorè N.I. IL-17A impairs host tolerance during airway chronic infection by Pseudomonas aeruginosa / N.I. Lorè, C. Cigana, C. Riva et al // Sci Rep. 2016 May 18;6:25937. doi: 10.1038/srep25937.

Lorè N.I. The IL-17A/IL-17RA axis in pulmonary defence and immunopathology / N.I. Lorè, A. Bragonzi, C. Cigana et al // Cytokine Growth Factor Rev. 2016 Aug;30:19;27. doi: 10.1016/j.cytogfr.2016.03.009.

Miyamoto M. Endogenous IL-17 as a mediator of neutrophil recruitment caused by endotoxin exposure in mouse airways / M. Miyamoto, O. Prause, M. Sjцstrand et al // J Immunol. 2003 May 1;170(9):4665-72. doi: 10.4049/jimmunol.170.9.4665.

Molofsky A.B. Interleukin-33 in Tissue Homeostasis, Injury, and Inflammation / A.B. Molofsky, A.K. Savage, R.M. Locksley // Immunity. 2015 Jun 16;42(6):1005-19. doi: 10.1016/j.immuni.2015.06.006.

Nakasone C. Limited role for interleukin-18 in the host protection response to pulmonary infection with Pseudomonas aeruginosa in mice / C. Nakasone, K. Kawakami, T. Hoshino et al // Infect Immun. 2004 Oct;72(10):6176-80. doi: 10.1128/IAI.72.10.6176-6180.2003.

Novick D. Interleukin-18, more than a Th1 cytokine / D. Novick, S. Kim, G. Kaplanski, C.A. Dinarello // Semin Immunol. 2013 Dec 15;25(6):439=48. doi: 10.1016/j.smim.2013.10.014.

Palomo J. Role of IL-1β in experimental cystic fibrosis upon P. aeruginosa infection / J. Palomo, T. Marchiol, J. Piotet et al // PLoS One. 2014 Dec 12;9(12):e114884. doi: 10.1371/jour;nal.pone.0114884.

Parker D. Induction of type I interferon signaling by Pseudomonas aeruginosa is diminished in cystic fibrosis epithelial cells / D. Parker, T.S. Cohen, M. Alhede et al // Am J Respir Cell Mol Biol. 2012 Jan;46(1):6-13. doi: 10.1165/rcmb.2011-0080OC.

Parker D. Innate Immune Signaling Activated by MDR Bacteria in the Airway / D. Parker, D. Ahn, T. Cohen, A. Prince // Physiol Rev. 2016 Jan;96(1):19-53. doi: 10.1152/physrev.00009.2015.

Patankar Y.R. Differential ASC requirements reveal a key role for neutrophils and a noncanonical IL-1β response to Pseudomonas aeruginosa / Y.R. Patankar, R. Mabaera, B. Berwin // Am J Physiol Lung Cell Mol Physiol. 2015 Oct 15;309(8):L902-13. doi: 10.1152/ajplung.00228.2015.

Pène F. Dendritic cells modulate lung response to Pseudomonas aeruginosa in a murine model of sepsis-induced immune dysfunction / F. Pène, B. Zuber, E. Courtine et al // J Immunol. 2008 Dec 15;181(12):8513-20. doi: 10.4049/jimmunol.181.12.8513.

Rathore J.S., Wang Y. Protective role of Th17 cells in pulmonary infection // Vaccine. 2016 Mar 18;34(13):1504-14. doi: 10.1016/j.vaccine.2016.02.021.

Roy S. CD14 mediates Toll-like receptor 4 (TLR4) endocytosis and spleen tyrosine kinase (Syk) and interferon regulatory transcription factor 3 (IRF3) activation in epithelial cells and impairs neutrophil infiltration and Pseudomonas aeruginosa killing in vivo / S. Roy, M. Karmakar, E. Pearlman // J Biol Chem. 2014 Jan 10;289(2):1174-82. doi: 10.1074/jbc.M113.523167.

Sawa T. IL-10 improves lung injury and survival in Pseudomonas aeruginosa pneumonia / T. Sawa, D.B. Corry, M.A. Gropper et al // J Immunol. 1997 Sep 15;159(6):2858-66. PMID: 9300709.

Schultz M.J. Interleukin-18 impairs the pulmonary host response to Pseudomonas aeruginosa / M.J. Schultz, S. Knapp, S. Florquin et al // Infect Immun. 2003 Apr;71(4):1630-4. doi: 10.1128/IAI.71.4.1630-1634.2003.

Schultz M.J. Role of interleukin-1 in the pulmonary immune response during Pseudomonas aeruginosa pneumonia / M.J. Schultz, A.W. Rijneveld, S. Florquin et al // Am J Physiol Lung Cell Mol Physiol. 2002 Feb;282(2):L285-90.

Shindo Y. Interleukin 7 immunotherapy improves host immunity and survival in a two-hit model of Pseudomonas aeruginosa pneumonia / Y. Shindo, A.G. Fuchs, C.G. Davis et al // J Leukoc Biol. 2016 Sep 14. pii: jlb.4A1215-581R.

Skerrett S.J. Role of the type 1 TNF receptor in lung inflammation after inhalation of endotoxin or Pseudomonas aeruginosa / S.J. Skerrett, T.R. Martin, E.Y. Chi et al // Am J Physiol. 1999 May;276(5 Pt 1):L715-27. PMID: 10330027.

Spight D. Immunoregulatory effects of regulated, lung-targeted expression of IL-10 in vivo / D. Spight, B. Zhao, M. Haas et al // Am J Physiol Lung Cell Mol Physiol. 2005 Feb;288(2):L251-65.

Sun L. Effect of IL-10 on neutrophil recruitment and survival after Pseudomonas aeruginosa challenge / L. Sun, R.F. Guo, M.W. Newstead et al // Am J Respir Cell Mol Biol. 2009 Jul;41(1):76-84. doi: 10.1165/rcmb.2008;0202OC.

Tsay T.B. Pseudomonas aeruginosa colonization enhances ventilator-associated pneumonia-induced lung injury / T.B. Tsay, Y.Z. Jiang, C.M. Hsu, L.W. Chen // Respir Res. 2016 Aug 9;17(1):101. doi: 10.1186/s12931-016-041-5.

Wölbeling F. Lung function and inflammation during murine Pseudomonas aeruginosa airway infection / F. Wцlbeling, A. Munder, T. Kerber-Momot et al // Immunobiology. 2011 Aug;216(8):901-8. doi: 10.1016/j.imbio.2011.02.003.

Wonnenberg B. The role of IL-1β in Pseudomonas aeruginosa in lung infection / B. Wonnenberg, M. Bischoff, C. Beisswenger et al // Cell Tissue Res. 2016 May;364(2):225-9. doi: 10.1007/s00441-016-2387-9.

Xiao M. The Role of Proinflammatory Cytokine Interleukin-18 in Radiation Injury // Health Phys. 2016 Aug;111(2):212-7. doi: 10.1097/HP.0000000000000494.

Xu X. Role of Interleukin-17 in defense against pseudomonas aeruginosa infection in lungs / X. Xu, B. Shao, R. Wang et al // Int J Clin Exp Med. 2014 Apr 15;7(4):809-16. PMID: 24955149.

Yue L. Protein Tyrosine Phosphatase-1B Negatively Impacts Host Defense against Pseudomonas aeruginosa Infection / L. Yue, Z. Xie, H. Li et al // Am J Pathol. 2016 May;186(5):1234-44. doi: 10.1016/j.ajpath.2016.01.005.