Effectiveness lisinopril and amlodipine combination in the prevention of patients with hypertonic disease in comorbidity witn obliterative atherosclerosis of lower extremities in family practice
##plugins.themes.bootstrap3.article.sidebar##
##plugins.themes.bootstrap3.article.main##
Abstract
The article presents the results of 40 patients with hypertonic disease (HD) with 2–3 degrees of arterial hypertension in combination with obliterative atherosclerosis of the lower extremities (OALE), in which hyperkinetic, eukinetic and hypokinetic types of central hemodynamics with the prevalence of the sympathetic nervous system were detected. It has been proved that in the absence of individual contraindications, the combination of an ACE inhibitor lisinopril and calcium antagonist amlodipine is optimal and universal for the effective treatment of patients with HD in combination with OALE in all types of central hemodynamics. Since after 6 months of treatment the highest positive dynamics of hemodynamic parameters, in particular, increase the pulse index – by 24,8%, the decrease in the resistance index – by 21,1%, the increase in the linear and volume velocity of blood – respectively, by 25,6% and 27,4% at the same time achievement of the target blood pressure level.
##plugins.themes.bootstrap3.article.details##
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors retain the copyright and grant the journal the first publication of original scientific articles under the Creative Commons Attribution 4.0 International License, which allows others to distribute work with acknowledgment of authorship and first publication in this journal.
References
Артеріальна гіпертензія. Стандарти надання медичної допомоги лікарями первинної ланки. – Укр. мед. Часопис. – 2018. – No 5 (127), т. 1, ІХ/Х. – С. 2–10.
Долженко М.М., Давидова І.В., Шершнева О.В. Європейські рекомендації з ведення хворих на артеріальну гіпертензію 2018: фокус на ішемічну хворобу серця / М.М. Долженко, І.В. Давидова, О.В. Шершнева // Здоров’я України. – 2018. – No 15–16 (436–437). – С. 35-37.
Наказ МОЗ України від 13.06.2016 р. No 564 «Уніфікований клінічний протокол первинної, вторинної (спеціалізованої) та третинної (високоспеціалізованої) медичної допомоги. Профілактика серцево-судинних захворювань». [Електронний ресурс]. Шлях доступу: http://moz.gov.ua/ua/portal/dn_20060703_436.html.
Волошина О.Б. Сучасні рекомендації щодо діагностики та лікування захворювань артерій нижніх кінцівок у практиці сімейного лікаря (огляд літератури) /О.Б. Волошина //Сімейна медицина. – 2017. – No 4 (72). – С. 48–54.
Сімейна медицина: навчальный посібник / [Гощинський В.Б., Бабінець Л.С., Стародуб Є.М. та ін.]; за ред. В.Б. Гощинського, Л.С. Бабінець, Є.М. Стародуба. – 2-е вид., доп. і перероб. – Тернопіль: ТДМУ, 2014. – 1162 с.
Шлант Р.К., Александер Р.В. Клиническая кардиология. – М.: СПб.: Издательство БИНОМ – Невский проспект, 2017. – 576 с.
ACC/AHA/AAPA/ABC/ACPM/AGS/ APhA/ASH/ASPC/NMA/PCNA guideline for the prevention, detection, evaluation, and management of high blood pressure in adults: a report of the American College of cardiology / American Heart Association Task Force on Clinical Practice Guidelines // Hypertension. – 2018. – Vol. 71, No 6. – P. 13–115.
ESC/ESH Guidelines for themanagement of arterial hypertension //European Heart Journal. – 2018. – Vol. 39, Issue 33. – P. 3021–3104.
ESC/EAS Guidelines for the Management of Dyslipidaemias: The Task Force for the Management of Dyslipidae-mias of the European Society of Cardiology (ESC) and European Atherosclerosis Society (EAS) Developed with the special contribution of the European Assocciation for Cardiovascular Prevention & Rehabilitation (EACPR) / A.L. Catapano, I. Graham, G. De Backer [et al.] // Eur. Heart J. – 2016. – Vol. 37 (38). – P. 2999–3058.
AHA/ACC/HHS strategies to enhance application of clinical practice guidelines in patients with cardiovascular disease and comorbid conditions: from the American Heart Association, American College of Cardiology, and U.S. Department of Health and Human Services/ Arnett D.K., Goodman R.A., Halperin J.L., et al./ Circulation. 2014; 130:1662–1667.
AHA/ACC Guideline on the Management of Patients With Lower Extremity Peripheral Artery Disease: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines/ M.D. Gerhard_Herman, H.L. Gornik, C. Barrett [et al.] // J.Am.Col. Cardiol. 2017 Mar 21; 69(11):1465–1508.
Peripheral arterial disease and critical limb ischaemia: still poor outcomes and lack of guideline adherence / H. Reinecke, M. Unrath, E. Freisinger [et al.] // Eur Heart J. 2015; 36: 932–938.
ESC Committee for Practice Guidelines. ESC Guidelines on the diagnosis and treatment of peripheral artery diseases: document covering atherosclerotic disease of extracranial carotid and vertebral, mesenteric, renal, upper and lower extremity arteries. The Task Force on the Diagnosis and Treatment of Peripheral Artery Diseases of the European Society of Cardiology (ESC) / M. Tendera, V. Aboyans, M.L. Bartelink [et al.] // Eur Heart J 2011;32:2851–2906.
World Health Organization. Global atlas on cardiovascular disease prevention and control. http://www.who.int/cardiovascular_diseases/publications/atlas_cvd/en/ Accessed August 12, 2014.
World Health Organization. Global Health Observatory: raised blood pressure. http://www.who.int/gho/ncd/risk_factors/blood_pressure_prevalence_text/en/ Accessed August 12, 2014.
