Сardiac tumors. Literature Review and the Clinical Case

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Published: May 31, 2019
DOI: https://doi.org/10.30841/2307-5112.2.2019.175683
Keywords:
benign cardiac tumors, cardiac myxoma, malignant cardiac tumors, clinical case,

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Б. М. Юрочко
Kyiv Railway Clinical Hospital No. 2, Ukraine
Л. І. Бурлакова
Kyiv Railway Clinical Hospital No. 2, Ukraine
С. М. Романов
Kyiv Railway Clinical Hospital No. 2, Ukraine

Abstract

Сardiac tumors are a rare pathology with a polymorphic clinical picture and the complexity of intravital diagnosis. All neoplasms of the heart are divided into primary benign (75% of all primary tumors) and malignant (25%), and secondary malignant tumors. Most cases among primary cardiac tumors are myxomas, which are more often localized in the left atrium (in 75% of cases). In addition to cardiac myxoma, a group of nonmyxomatous benign heart tumors is distinguished: rhabdomyomas, fibromas, lipomas, leiomyomas, angiomas, neurinomas and others. Primary malignant neoplasms are mainly represented by sarcomas. Secondary (metastatic) neoplasms occur 13–40 times more often than primary tumors. Clinical manifestations of cardiac tumors depend on the infringement of inflow or outflow from the affected heart chambers, the presence of an embolic syndrome, the general reaction of the organism to a tumor. Echocardiography is the main research method for the initial diagnosis of cardiac tumors, which pelps to determine the size of the tumor, localization, attachment site, mobility, the relationship with the valve apparatus and the character of hemodynamics. Modern methods of research use magnetic resonance imaging and computed tomography. Treatment of benign heart tumors is surgical. In the treatment of malignant tumors, three methods are used: surgical, radiation and chemotherapy. The article presents the clinical case of a patient with a left atrial and pericardial tumor without obstruction of blood flow.

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How to Cite
Юрочко, Б. М., Бурлакова, Л. І., & Романов, С. М. (2019). Сardiac tumors. Literature Review and the Clinical Case. Family Medicine, (2), 113–119. https://doi.org/10.30841/2307-5112.2.2019.175683
Issue
No. 2 (2019)
Section
Literature review
Copyright (c) 2020 Б. М. Юрочко, Л. І. Бурлакова, С. М. Романов

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This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors retain the copyright and grant the journal the first publication of original scientific articles under the Creative Commons Attribution 4.0 International License, which allows others to distribute work with acknowledgment of authorship and first publication in this journal.

References

Бураковский В.И., Бокерия Л.А. Сердечно-сосудистая хирургия.– М.: Медицина, 1989. – С. 457–464.

Кипренский А.Ю., Нечаенко М.А. Диагностика и хирургическое лечение немиксоматозных опухолей сердца // Казанский мед. журн. – 2014. – Т. 95, № 6. – С. 821–830.

Кнышов Г.В., Витовский Р.М., Захарова В.П. Опухоли сердца. – К.: Пресса України, 2005. – 256 с.

Кнышов Г.В., Витовский Р.М., Захарова В.П., Лозовой А.А. Опыт хирургического лечения миксомы сердца // Український кардіологічний журнал. – 1997. – № 5–6. – С. 23–26.

Лозовой А.А. Миксомы сердца (клиника, диагностика, хирургическое лечение, отдаленные результаты). Дис. канд. мед. наук. – К., 1986. – 144 с.

Нечаенко М.А., Кузнецова Л.М., Овчинникова В.И. и др. Первичные опухоли сердца // Хирургия. – 1999. – № 8. – С. 23–27.

Петровский Б.В., Константинов Б.А., Черепенин Л.П. и др. Хирургия внутриполостных опухолей сердца // Хирургия. – 1985. – № 4. – С. 10–17.

Anvari M.S., Naderan M. et al. Clinicopathologic review of non-mixoma cardiac tumors: a 10-year single-center experience // Cardiology. – 2014. – Vol. 129. – P. 199–202.

Araoz P.A., Mulvagh S.L., Tazelaar H.D. et al. CT and MR imaging of benign primary cardiac neoplasms with echocardiographic correlation // Radiographics. – 2006. – Vol. 20. – P. 1303–1319.

Basso C., Valente M., Poletti A. et al. Surgical pathology of primary cardiac and pericardial tumors // Eur. J. Cardio-Thorac. Surg. – 1997. – Vol. 12, № 5. – P. 730–737.

Bastos P., Barreiros F., Casanova J., Gomes M.R. Cardiac myxomas: surgical treatment and long-term results // Cardiovascular Surgery. – 1995. – Vol. 3, № 6. – P. 595–597.

Burazor I., Avielronen S., Imazio M. et al. Primary malignancies of the heart and pericardium // Clin. Cardiol. – 2014. – Vol. 37. – P. 582–588.

Butany J., Nair V., Naseemuddin A. et al. Cardiac tumors: diagnosis and management // The Lancet Oncology. – 2005. – Vol. 6, № 4. – P. 219–228.

Chakfe N., Kretz J.G., Valentin P. et al. Clinical presentation and treatment options for mitral valve myxoma // Ann. Thorac. Surg. – 1997. – Vol. 34, № 3. – P. 872–877.

Cis A., Fernandez Rostello E., Marticani R. Myxoma of the left ventricular outflow tract //An. Esp. Pediatr. – 2001. – Vol. 55, № 1. – P. 80–82.

Di Liang C., Ko S.F., Huang S.C. Echocardiographic evaluation of cardiac rhabdomyoma in infants and children // J. Clin Ultrasound. – 2000. – Vol. 28, № 8. – P. 381–386.

Endo A., Ohtahara A., Kinugawa T. et al. Clinical incidence of primary cardiac tumors // Journal of Cardiology. – 1996. – Vol. 28, № 4. – P. 227–234.

Fang B.R., Chiang C.W., Hung J.S. et al. Cardiac myxoma – clinical experience in 24 patients // Int. J. Cardiol. – 1990. – Vol. 29, № 3. – P. 335–341.

Goswami K.C., Shrivastava S., Bahl V.K. et al. Cardiac myxomas: clinical and echocardiographic profile // International Journal of Cardiology. – 1998. – Vol. 63, № 3. – P. 251–259.

Grande A.M., Ragni T., Vigano M. Primary cardiac tumors. A clinical experience of 12 years // Tex. Heart. Inst. J. – 1993. – Vol. 20, № 3. – P. 223–230.

Harada T., Ohtaki E., Sumiyoshi T., Hosoda S. // Successful threedimensional reconstruction using transesophageal echocardiography in a patient with a left atrial myxoma // Jpn. Heart J. –2001. – Vol. 42, № 6. – P. 789–792.

Ji-Gand Wang, Baolei Wang, Yanjiano Hu et al. Clinicopathologic features and outcomes of primary cardiac tumors: a 16-year-experience with 212 patients at a Chinese medical center // Cardiovascular Pathology. – 2018. – Vol. 33. – P. 45–54.

Majono-Lainez R.A. Cardiac tumors: a current clinical and pathological perspective // Critical Reviews in Oncogenesis. – 1997. – Vol. 8, № 4. – P. 293–303.

Meng Q., Lai H., Lima J. et al. // Echocardiographic and pathologic characteristics of primary cardiac tumors: a study of 149 cases // Int. J. Cardiol. – 2013. – Vol. 84, № 1. – P. 69–75.

Oliveira G.H., AlKindi S.G., Hoimes C. et al. Characteristics and survival of malignant cardiac tumors // Circulation. – 2015. – Vol. 132. – P. 2395–2402.

Perchinsky M.J., Lichtenstein S.V., Tyers GF. Primary cardiac tumors: forty years’ experience with 71 patients // Cancer. – 1997. – Vol. 79, № 9. – P. 1809–1815.

Puvaneswary M., Thomson D. Magnetic resonance imaging features of an infected right atrial myxoma // Australas. Radiol. – 2001. – Vol. 45, № 4. – P. 501–503.

Reyen K., Daniel W.G. Images in cardiovascular medicine. Cardiac myxoma // Circulation. – 1996. – Vol. 94, № 5. – P. 1137.

Ryan PE Jr, Obeid Al, Parker FB Jr. Primary cardiac valve tumors // J. Heart Valve Dis. – 1995. – Vol. 4, № 4. – P. 222–226.

Schmid C., Paterakis S., Likungu J.A. et al. Cardiac myxoma. Clinical and pathologic features in 15 cases // Klin. Wochenschr. – 1988. – Vol. 66, № 16. – P. 713–717.

Simpson L., Kumar S.K., Okuno S.H. et al. Malignant primary cardiac tumors: review of a single institution experience // Cancer. – 2008. – Vol. 112 (11). – P. 2440–2446.

Smith D.N., Shaffer K., Patz E.F. Imagin features of nonmyxomatous primary neoplasms of the heart and pericardium // Clinical Imaging – 1998. – Vol. 22, № 1. – P. 15–22.

Sommer T., Vahlhaus C., Hofer U., et al. MRI diagnosis of 146 cardiac myxomas: sequence evaluation and differential Diagnosis // Rofo Fortschr. Geb. Rontgenstr. Neuen Bildgeb. Verfahr. – 1999. – Vol. 170, № 2. – P. 156–162.

Spartalis M., Tzatzaki E., Spartalis E. et al. Atrial myxoma mimicking mitral stenosis // Cardiol Res. – 2017. – Vol. 8, № 3. – P. 128–130.

St John Sutton M.G., Marcier L.A., Giuliani E.R., Lie J.T. Atrial myxomas: A rivew of clinical experience in 40 patients // Mayo Clin Proc. – 1980. – Vol. 55. – P. 371–376.

Tiraboschi R., Terzi A., Merlo M., Procopio A. Left atrial myxoma. Clinical and surgical features in 26 surgically treated cases // Ital Heart J. – 2000. – Vol. 1, № 6. – P. 797–802.

Vander Salm T.J. Unusual primary tumors of the heart // Semin Thorac Cardiovasc Surg. – 2000. – Vol. 12, № 8. – P. 89–100.

Voegele L.D., Prioleau W.H., Locklair P.R., Bradham R.R. Atrial myxoma: diagnosis and treatment // Journal – South Carolina Medical Association. – 1995. – Vol. 91, № 3. – P. 89–92.

Zheng Z., Guo G., Xu L., et al. Left atrial myxoma with versus without cerebral embolism: length of symptoms, morphologic characteristics, and outcomes // Tex. Heart Inst. J. – 2014. – Vol. 41, № 6. – P. 592–595.