The Issue of Rational Use of Antibiotics in the Treatment of Urinary Tract Infection and the Strategy of Antibiotic Resistance Management

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Т. В. Буднік

Abstract

The article focuses on the abuse of antibacterial drugs in patients with urinary tract infections, both in the adult population and in children. In today’s era of large-scale antibiotic resistance, such tactics are not only ineffective for the patient, but also detrimental to the population as a whole. The optimal clinical decision is stratification of the patient with urinary tract infections for the appointment of an antibiotic or the use of another alternative with proven efficacy, such as officinal urological vaccine Urivac.

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How to Cite
Буднік, Т. В. (2019). The Issue of Rational Use of Antibiotics in the Treatment of Urinary Tract Infection and the Strategy of Antibiotic Resistance Management. Family Medicine, (1), 19–24. https://doi.org/10.30841/2307-5112.1.2019.172040
Section
Topical issues
Author Biography

Т. В. Буднік, P.L. Shupyk National Medical Academy of Postgraduate Education

Tetiana V. Budnik,

Department of Nephrology and Renal Replacement Therapy

References

Захарова И.Н., Османов И.М., Мумладзе Э.Б., Мачнева Е.Б., Тамбиева Е.В., Бекмурзаева Г.Б. Бессимптомная бактериурия: смена общепринятого взгляда. Медицинский совет, 2017, 19: 162–167. https://doi.org/10.21518/2079-701X-2017-19-162-167

Коган М. И., Набока Ю. Л., Ибишев Х. С., Гудима И. А. Нестерильность мочи здорового человека – новая парадигма в медицине // Урология. – 2014. – № 5.– С. 48–52.

Robinson JL, Finlay JC, Lang ME, Bortolussi R. Urinary tract infections in infants and children: Diagnosis and management. Canadian Paediatric Society, Infectious Diseases and Immunization Committee, Community Paediatrics Committee. Paediatr Child Health, 2014 Jun, 19(6): 315–25. https://doi.org/10.1093/pch/19.6.315

Finucane TE. «Urinary Tract Infection» – Requiem for a Heavyweight. J Am Geriatr Soc, 2017 Aug 65(8): 1650–1655. https://doi.org/10.1111/jgs.14907

Curtiss N, Balachandran A, Krska L, Peppiatt Wildman C, Wildman S, Duckett J. Age, menopausal status and the bladder microbiome. Eur J Obstet Gynecol Reprod Biol. 2018 Jun 18 228: 126–129. https://doi.org/10.1016/j.ejogrb.2018.06.011

Komesu YM, Richter HE, Carper B, Dinwiddie DL, Lukacz ES, Siddiqui NY, Sung VW, Zyczynski HM, Ridgeway B, Rogers RG, Arya LA, Mazloomdoost D, Gantz MG. The urinary microbiome in women with mixed urinary incontinence compared to similarly aged controls. Int Urogynecol J. 2018 Dec; 29(12):1785–1795. https://doi.org/10.1007/s00192-018-3683-6

Karstens L, Asquith M, Davin S, Stauffer P, Fair D, Gregory WT, Rosenbaum JT, McWeeney SK, Nardos R. Does the Urinary Microbiome Play a Role in Urgency Urinary Incontinence and Its Severity? Front Cell Infect Microbiol, 2016 Jul 27,6:78. https://dx.doi.org/10.3389%2Ffcimb.2016.00078

Vila J, Sáez-López E, Johnson JR, Römling U, Dobrindt U, Cantón R, Giske CG, Naas T, Carattoli A, Martínez-Medina M, Bosch J, Retamar P, Rodríguez-Baño J, Baquero F, Soto SM. Escherichia coli: an old friend with new tidings. FEMS Microbiol Rev, 2016 Jul 1, 40(4): 437–463. https://doi.org/10.1093/femsre/fuw005

Fouts D.E., Pieper R., Szpakowski S., Pohl H., Knoblach S., Suh M.J., Huang S.T., Ljungberg I., Sprague B.M., Lucas S.K., Torralba M., Nelson K.E., Groah S.L. Integrated next-generation sequencing of 16S rDNA and metaproteomics differentiate the healthy urine microbiome from asymptomatic bacteriuria in neuropathic bladder associated with spinal cord injury. J Transl Med 2012; 10: 174. https://doi.org/10.1186/1479-5876-10-174

Ingersoll M.A., Albert M.L. From infection to immunotherapy: host immune responses to bacteria at the bladder mucosa. Mucosal Immunol 2013; 6(6): 1041–1053. https://doi.org/10.1038/mi.2013.72

Wu X.R., Kong X.P., Pellicer A., Kreibich G., Sun T.T. Uroplakins in urothelial biology, function, and disease. Kidney Int 2009; 75(11): 1153–1165. https://doi.org/10.1038/ki.2009.73

Shin K., Lee J., Guo N., Kim J., Lim A., Qu L., Mysorekar I.U., Beachy P.A. Hedgehog/Wnt feedback supports regenerative proliferation of epithelial stem cells in bladder. Nature 2011; 472(7341): 110–114. https://doi.org/10.1038/nature09851

Hicks R.M. The mammalian urinary bladder: an accommodating organ. Biol Rev Camb Philos Soc 1975; 50: 215–246. https://doi.org/10.1111/j.1469-185X.1975.tb01057.x

Darouiche R.O., Hull R.A. Bacterial interference for prevention of urinary tract infection. Clin Infect Dis 2012; 55: 1400–1407. https://doi.org/10.1093/cid/cis639

Wolfe A. J., Brubaker L. «Sterile Urine» and presence of bacteria // European Urology, 2015 Aug; 68(2):173–4. https://doi.org/10.1016/j.eururo.2015.02.041

Lewis D.A., Brown R., Williams J. et al. The human urinary microbiome; bacterial DNA in voided urine of asymptomatic adults // Front. Cell Infect. Microbiol. 2013; 3: 41. https://doi.org/10.3389/fcimb.2013.00041

Stein R, Dogan HS, Hoebeke P et al. Urinary Tract Infections in Children: EAU/ ESPU Guidelines. Eur Urol, 2015 Mar; 67(3):546–58. https://doi.org/10.1016/j.eururo.2014.11.007

Miroslav Hanuš, Michaela Matoušková Vlasta Králová, Jan Hiblbauer jr., Jakub Szewczyk, Radek Sýkora, Riad Sabra, Peter Tomaštík, Jiří Paseka / Imunostimulace polybakteriálním lyzátem (Urivac®) v prevenci recidivujících infekcí dolních močových cest // Česká urologie, 2015 (roč. 19), číslo 1.