The prediction of pneumonia in patients with immunity disorders on the background of onkolohematological pathology
##plugins.themes.bootstrap3.article.sidebar##
##plugins.themes.bootstrap3.article.main##
Abstract
In the study, on the basis of statistical analysis of the complex of clinical-laboratory, anamnestic and immunological parameters of 495 patients, predictors of pneumonia were determined and a logistic model of the prediction of the occurrence of pneumonia in patients with immune disorders on the background of oncohematological pathology was developed, which included indicators that are characteristics of the course of oncological diseases of the blood, as well as indicators of immune reactivity.
##plugins.themes.bootstrap3.article.details##
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors retain the copyright and grant the journal the first publication of original scientific articles under the Creative Commons Attribution 4.0 International License, which allows others to distribute work with acknowledgment of authorship and first publication in this journal.
References
Torres A., Niederman M.S., Chastre J. International ERS/ESICM/ESCMID/ALAT guidelines for the management of hospital-acquired pneumonia and ventilator-associated pneumonia: Guidelines for the management of hospital-acquired pneumonia (HAP)/ventilator-associated pneumonia (VAP) of the European Respiratory Society (ERS), European Society of Intensive Care Medicine (ESICM), European Society of Clinical Microbiology and Infectious Diseases (ESCMID) and Asociación Latinoamericana del Tórax (ALAT). Eur. Respir J. 2017; 50 (3). https://doi.org/10.1183/13993003.00582-2017
Guidelines for the management of adults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia. J. Respir. Crit. Care Med. 2005; 171: 388–416. https://doi.org/10.1164/rccm.200405-644ST
Management of Adults With Hospital Acquired and Ventilator-associated Pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of America and the American Thoracic Society. https://dx.doi.org/10.1093%2Fcid%2Fciw353
Nakaz MOZ Ukraїni «Pro zatverdzhennya klіnіchnikh protokolіv nadannya medichnoї dopomogi za spetsіal’nіstyu «Pul’monologіya» [Unorthodontic and nosocomial (hospital) pneumonia in adults: etiology, pathogenesis, classification, diagnosis, antibiotic therapy (methodical recommendations)]. K.: Veles. 2007:105–146р. Ukrainian.
Natsіonal’na akademіya nauk Ukraїni. Tsentr medichnoї statistiki Ukraїni MOZ Ukraїni. Derzhavna ustanova «Natsіonal’niy іnstitut ftizіatrії і pul’monologії іm. F.G. Yanovs’kogo AMN Ukraїni» [Portovnyalny dany about rozpovsuzhenzhenost zabor organiiv dihannya I medichnu dopomogu govorim pulmonologіchnogo profilju in Ukraini for 2008-2014 rr.]. Kiїv. 2014. Ukrainian. http://www.ifp.kiev.ua/doc/staff/pulmukr2014.pdf
Cancer Facts & Figures. GA: American Cancer Society. 2017. https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/annual-cancer-facts-and-figures/2017/cancer-facts-and-figures-2017.pdf
Sivkovych S.O., Zinchenko V.N., Zubryts’ka T.B. State of medical care of patients with hematological malignancies in Kyїv. Lik Sprava. 2012 Dec;(8):134–40.
[Clinical immunology and allergology]. 2011:550 р. Ukrainian.
Voytsekhovskiy V.V., Esenina T.V., Filatova E.A., Makarova N.V. [Infectious complications of hemoblastoses during programmed chemotherapy]. Amurskiy meditsinskiy zhurnal. 2011; 6:10–20. Russian.
Toropova I.Yu., Parovichnikova E.N., Klyasova G.A. [Clinical monitoring of infectious complications in patients with hemoblastomas on the background of programmed chemotherapy] Gematologiya i transfuziologiya. 2011; 6: 10–20. Russian.
Lekhan V.M., Voronenko Yu.V., Maksimenko O.P. [Epidemiological methods for the study of non-infectious diseases: a manual]. 2004, 184 p. Ukrainian.
Nakaz MOZ Ukraїni «Pro zatverdzhennya protokolіv nadannya medichnoї dopomogi za spetsіal’nіstyu «Onkologіya» vіd 30.07.2010 r. № 647 іz dopovnennyami zgіdno: Nakazu MOZ Ukraїni vіd 30.01.2013 № 72; Nakazu MOZ Ukraїni vіd 02.11.2015 № 709; Nakazu MOZ Ukraїni vіd 02.11.2015 № 711; Nakazu MOZ Ukraїni vіd 02.11.2015 № 710; Nakazu MOZ Ukraїni vіd 26.06.2014 № 433. [Standards of diagnosis and treatment of cancer patients]. Ukrainian.
Lang T.A. [How to describe statistics in medicine. Guidelines for authors, editors and reviewers]. Moskva: Prakticheskaya meditsina. 2016: 480 р. Russian.
Šimundić A.M. Measures of Diagnostic Accuracy: Basic Definitions. EJIFCC. 2009; 19(4): 203–211.
Pertseva T.O., Borisova І.S. [Peculiarities of the course of pneumonia in patients with immune disorders in hemoblastoses]. Medichnі perspektivi. 2012; 1:32–39. Ukrainian.
Taj M., Farzana T., Shah T. Clinical and Microbiological Profile of Pathogens in Febrile Neutropenia in Hematological Malignancies: A Single Center Prospective Analysis. Journal of Oncology. 2015: 5. http://dx.doi.org/10.1155/2015/596504
Bakulina E.S. [Features of hemopoietic disorders in patients with multiple myeloma on the background of cytostatic therapy with alkeran-containing regimens and bortezomib]. Аvtoref. dis. na zdobuttya stupenya kand. med. nauk : spets. 14.01.21 Gematologiya i perelivanie krovi” Moskva. 2013, 25. Russian.
Peshikova M.V. [Clinical and immunological features of infectious complications in children with acute lymphoblastic leukemia and non-B-cell non-Hodgkin’s lymphomas receiving chemotherapy according to the BFM-ALL-90 protocol (M)]. Аvtoref. dis. na zdobuttya stupenya kand. med. nauk. Chelyabinsk. 2004: 24 р. Russian.
