The Use of Harpagophytum Procumbens (Martynia Fragrans) in Rheumatology: a Look through the Prism of Comorbidity (Literature Review)


О. І. Волошин
С. І. Сміян
Л. О. Волошина
С. С. Горевич


The objective: is to highlight the scientific achievements of the use of Harpagophytum procumbens in patients with osteoarthritis and other rheumatic diseases, including the aspect of comorbid processes inherent in this pathology.

Materials and methods. The authors conducted a research in printed and electronic publications, science research bases, the State Register of Medicinal Products of Ukraine using methods of analysis, comparison and synthesis of information data, as well as the results of their own initial studies of the efficacy of Harpagophytum procumbens in patients with osteoarthritis with phenomena comorbid processes.

Results. Materials of scientific researches carried out in different countries of the world testify that the extract of Martynia Fragrans has a multifaceted therapeutic effect of patients with osteoarthritis and age-old comorbid processes due to the properties of this plant like hypotensive, cardiotonic, disaggregant, hypoglycemic, choleretic, which improves the digestive system and kidneys qualities. The indicated properties of drugs with Martynia Fragrans are important in terms of a possible beneficial effect on comorbid diseases of the cardiovascular, digestive, genitourinary systems and diabetes mellitus, which occur in patients with osteoarthritis. A further prospect of clinical research in this direction is presented, which will be in line with the main principles of the «Strategy of the World Health Organization in the field of traditional medicine for 2014–2023».

Conclusions. Preparations of Martynia (Harpagophytum procumbens) root have a multifaceted mechanism of action and are effective and safe in the treatment of patients with osteoarthritis, arthritis, mild and moderate pains. Achievements of traditional medicine and the latest studies of the effects of the extracts of Martynia Fragrans on metabolism, other organs and systems provide prospects for their positive impact on comorbid diseases in osteoarthritis and improve the overall results of treatment of such patients, being the prospects for further research.


How to Cite
Волошин, О. І., Сміян, С. І., Волошина, Л. О., & Горевич, С. С. (2020). The Use of Harpagophytum Procumbens (Martynia Fragrans) in Rheumatology: a Look through the Prism of Comorbidity (Literature Review). Family Medicine, (3), 93–97.
Lectures and reviews
Author Biographies

О. І. Волошин, Bukovinian State Medical University

Oleksandr I. Voloshуn,

Department of Propaedeutics of Internal Diseases

С. І. Сміян, I. Horbachevsky Ternopil State Medical University

Svitlana I. Smiyan,

Department of Internal Medicine No 2

Л. О. Волошина, Bukovinian State Medical University

Larysa O. Voloshуna,

Department of Internal Medicine and Infectious Diseases

С. С. Горевич, Bukovinian State Medical University

Svitlana S. Horevуch,

Department of Propaedeutics of Internal Diseases


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