DOI: https://doi.org/10.30841/2307-5112.2.2019.175181

Features of the Lipid Profile in Different Activity of the Components of the Renin-angiotenzin-aldosterone System in Patients with Essential Hypertention and Obesity

М. М. Кочуєва, В. Г. Псарьова, Н. М. Кириченко, Л. А. Рубан, Г. І. Кочуєв, А. С. Шалімова

Abstract


The objective: the aim of the study was to evaluate the features of the lipid profile in the case of different activity of the components of the renin-angiotensin-aldosterone system in patients with arterial hypertension (AH) and concomitant obesity.

Materials and methods.188 patients with essential hypertension (EH) and obesity I–II degrees were examined (who gave informed written consent to participate in the study and met the inclusion criteria). The control group consisted of 25 practically healthy individuals, matched by age and sex with the main group patients.

Results. It was established that in patients with comorbidity of EH and obesity I–II degrees, the low-renin AH (LRAH) was found in 9,4% of cases. The LRAH and high-renin AH (HRAH) in obese patients did not differ in anthropometric indices.

Conclusion. In the presence of LRAH in patients with obesity I–II degrees the levels of atherogenic lipoproteins were significantly lower than in HRAH.

Keywords


arterial hypertension; obesity; renin-angiotensin-aldosterone system; low-renin hypertension; lipid profile

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Copyright (c) 2020 М. М. Кочуєва, В. Г. Псарьова, Н. М. Кириченко, Л. А. Рубан, Г. І. Кочуєв, А. С. Шалімова

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