The Influence of Combined Therapy on Lipid, Glucose Profile in Patients with Diabetes Mellitus Type II

Authors

  • О. П. Федорова Training-Scientific Center «University Clinic» of Zaporizhzhia State Medical University
  • О. В. Дудко Training-Scientific Center «University Clinic» of Zaporizhzhia State Medical University
  • О. А. Світлицька Training-Scientific Center «University Clinic» of Zaporizhzhia State Medical University
  • Т. І. Кікнадзе Training-Scientific Center «University Clinic» of Zaporizhzhia State Medical University

DOI:

https://doi.org/10.30841/2307-5112.5.2018.168204

Keywords:

diabetes mellitus type II, Insuvit, diabetic polyneuropathy

Abstract

According to the International Federation of Diabetes, 7% of the population of the world suffers from diabetes. Optimizing the treatment of diabetes with herbal medicines will reduce the patient’s drug burden.

The objective: the aim of the study was to assess the efficacy of combined treatment with the complex vitamin-herbal pills Insuvit, Metformin and Atorvastatin in patients with diabetes mellitus type II.

Materials and methods. 69 patients (women – 44, men – 25) were treated with diabetes mellitus type II in the therapeutic department of the University Hospital of the ESMC «University Clinic». The average age was 63,4±7,82 years, the duration of diabetes – 7,0±4,11 years. Fasting blood glucose levels, glycosylated hemoglobin (HbA1c), lipid profile were determined onset. Patients were randomized on 2 groups: the main group – 33 patients, who received additionally Insuvit (1 tablet twice a day) for 12 weeks to standard therapy (20 mg of Atorvastatin, 1000 mg of Metformin). Control – 36 patients with similar therapy, but without the appointment of Insuvit.

Results. The levels of HbA1c (by 10,7%), glucose (by 14,7%) and triglycerides (by 35,4%) (p<0,05) significantly decreased after 12 weeks therapy in the main group in comparison with control group. In 39,4% patients of the main group there was s decrease in the sensation of paresthesias, which led to an improvement in overall well-being.

Conclusions. The additional use of the drug Insuvit accelerates the compensation of glucose and HbA1c levels in patients with diabetes mellitus type II, which allows them to reach their target levels more quickly.

Author Biographies

О. П. Федорова, Training-Scientific Center «University Clinic» of Zaporizhzhia State Medical University

Olena P. Fedorova,

Department of Family Medicine, Therapy, Cardiology and Neurology at the Faculty of Postgraduate Education

О. В. Дудко, Training-Scientific Center «University Clinic» of Zaporizhzhia State Medical University

Olena V. Dudko,

Head of Therapeutics Department

О. А. Світлицька, Training-Scientific Center «University Clinic» of Zaporizhzhia State Medical University

Oksana A. Svetlitzskaya,

Department of Family Medicine, Therapy, Cardiology and Neurology at the Faculty of Postgraduate Education

Т. І. Кікнадзе, Training-Scientific Center «University Clinic» of Zaporizhzhia State Medical University

Tetiana I. Kiknadze,

Therapeutics Department

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Published

2018-11-30

Issue

Section

Endocrinology