DOI: https://doi.org/10.30841/2307-5112.4(72).2017.117764

Indicators of the system of free radial oxidation in patients with diabetes mellitus after maloinvasive treatment with ureterolytiaase induction

А. Ю. Гурженко

Abstract


The objective: to determine the state of free radical oxidation in people with ureterolithiasis and concomitant diabetes mellitus undergoing various methods of minimally invasive surgical treatment of urinary stones.

Patients and methods. The study involved 164 patients and 12 healthy volunteers, of whom men accounted for 93 (56,7%), women –  71 (43,3%) persons. The age range of patients is 19–53 years, on aver age – 34,6±5,5 years. The average age of women is 30,1±2,9 years, and men are 37,6±3,1 years. Patients were divided into IV clinical groups: I – patients with ureterolithiasis and diabetes, which were performed by TUKL (n=34); II – patients with ureterolithiasis and diabetes, which were conducted by the EWHL (n=32); III – patients with ureterolithiasis without diabetes, which was performed by TUKL (n=41); IV – patients with ureterolithiasis without diabetes, which  was performed by ESWL (n=57). The control group consisted of healthy volunteers with no signs of pathology (n=12). The studies were performed before and after disintegration of stones by the method of transurethral contact lithotripsy (TUKL) and ESWL.

Results. Conducting an analysis of the indicators of the VR system, the dependence of their displacements on the severity of violations in other parts of the homeostasis and the stage of the DN, provides opportunities for a more complete assessment of the patient’s condition, with the establishment of prospects for treatment under these clinical conditions.

Conclusion. Indicators of metabolic homeostasis reflect the intense processes of the LPO AOP system, which in the case of ureterolithia sis in persons with diabetes mellitus are in most cases uncompensated and are characterized by high risk of development of side effects in the case of the use of the method of ESWL, in contrast to the TUKL technique.


Keywords


ureterolithiasis; diabetes mellitus; free radical oxidation; lithotripsy contact; distant lithotripsy

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