DOI: https://doi.org/10.30841/2307-5112.1(69).2017.103219

Study of the effeciency and feasibility of including Kuplaton and Rehydron Optim in complex treatment regimens of patients with chronic pancreatitis

С. Є. Шостак

Abstract


The objective: to study the effeciency and feasibility of intcluding Regidron Optim and Kuplaton in complex regimens of patients with chronic pancreatitis (CP) in the treatment on an outpatient basis. Patients and methods. The study involved 62 patients with CP, 15 women and 47 men, average age was 50,71±1,71 years. The patients were divided into two randomized comparison groups. First (I) group received only basic therapy. II group additionally took studied drugs. The data of general clinical investigations, laboratory and instrumen tal parameters were studied during treatment. Results. Regress of subjective and objective manifestations of CP was more rapid in patients of group II. Also there were a significant improvement in functional status of pancreas and organs of hepatobil iary zone in group II. There was fast reducing of amylase level in serum and urine, total bilirubin and transaminase levels in patients of this group. This changes statistically decreased in comparison with indica tors before treatment and with parameters of first examined group. Conclusion. Thus, the inclusion of Regidron Optim and Kuplaton in complex treatment regimens of patients with chronic pancreatitis allowed to significantly accelerate the dynamics of subjective and objective symptoms of diseases. It improves laboratory and instrumen tal performance. Also it provides a better understanding between doc tor and patient, which significantly differ from patients receiving only basic therapy.

Keywords


Regidron Optim; Kuplaton; chronic pancreatitis; treatment

References


Italian consensus guidelines for chronic pancreatitis / L. Frulloni, M. Falconi, A. Gabrielli et al. // J. Digestive and Liver Diasease. – 2010. –Vol. 42, Suppl. 6. – P. S381–S406.

Guideline for the diagnosis and treatment of chronic pancreatitis / P.C. Bornman, J.E. Botha, J.M. Ramos et al // SAMJ. – 2010. – Vol. 100, No 12. – P. 547–859.

Management of pancreatic exocrine insufficiency; Australasian Pancreatic Club recommendations / J. Toouli, A.V. Biankin, M.R. Oliver et al. // MJA. – 2010. – Vol. 193, No 8. – P. 461–467.

Guidelines for diagnosis and treatment of chronic pancreatitis. Recommendations of the Working Group of the Polish National Consultant in Gastroenterology and the Polish Pancreatic Club / K. Їuk, E. Czkwianiank, M. Degovska et al. // PrzeglNod Gastroenterologiczny. – 2011. – Vol. 6, No 6. – Р. 339–352.

Кучерявый Ю.А. Пациент с хроническим панкреатитом: ошибки ведения, возможные причины и пути решения // Гастроэнтерология. – Приложение Consilium medicum – 2011; 1: 46–55.

Наказ МОЗ України від 10.09.2014 No 638 «Про затвердження та впровадження медико технологічних документів зі стандартизації медичної допомоги при хронічному панкреатиті».

Губергриц Н.Б. Неалкогольная жировая болезнь поджелудочной железы / Н.Б. Губергриц, Т.Н. Христич, О.А. Бондаренко. – Донецк: ООО «Лебедь», 2013. – 236 с.

Губергріц Н.Б. Лікування хронічного панкреатиту / Н.Б. Губергріц, О.О. Голубова // Раціональна фармакотерапія. – 2007. – No 2. – С. 33–36.

Губергріц Н.Б. Практична панкреатологія / Н.Б. Губергріц, С.В. Скопіченко. – Донецьк: Либідь, 2007. – 244 с.

Lindkvist B. Diagnosis and treat ment of pancreatic exocrine insufficiency // World J. Gastroenterol. – 2013. – Vol. 19(42). – P. 7258–7266.

Seokyung Hahn, Yaejean Kim, Paul Garner Reduced osmolarity oral rehydration solution for treating dehydration caused by acute diarrhoea in children Cochrane Library. – 2002. – Issue 1.

Hahn S, Kim Y, Garner P. Reduced osmolarity oral rehydration salts solution for treating diarrhoea associated dehydration in children: systematic review. British Medical Journal. – 2001. – No 323. – Р. 81–5.

Guarino A, Albano F, Guandalini S. Oral rehydration: Toward a real solution. Journal of Pediatric Gastroenterology and Nutrition. – 2001. – No 33 (4). – Р. 2–12.

Малый В.П. Холера: клиника, диагностика, лечение // Здоров’я України. – 2011. – No 4. – С. 5–16.

Малый В.П., Лядова Т.И., Шустваль Н.Ф. Пищевые токсикоинфекции и интоксикации: монография. Харьков: «Апостроф», 2011. – 212 c.

Котлова Ю.В., Курочкина Т.И., Крыгина А.Н. Эффективная симптоматическая терапия метеоризма у недоношенных новорожденных детей // Современная педиатрия. – 2009. – No 4. – С. 157–158.




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